Seeking romance

#1 I’ve been single-stranded too long! Lonely ATGCATG would like to pair up with congenital TACGTAC.

#2 Menage a trois! Ligands seeks two receptors into binding and mutual phosphorylation. Let’s get together and transduce some signals.

#3 Some dates have called me a promotor. Others have referred to me as a real operator. Personally, I think I’m just a cute piece of DNA who is still looking for that special transcription factor to help me unwind.

#4 Highly sensitive, orally active small molecule seeks stable well-structured receptor who knows size isn’t everything.

#5 There must be a rational way to meet a date! I’m tired of hanging out in those molecular diversity bars, hoping to randomly bump into the right peptide. I want a molecule that will fit right onto my active site and really turn me on. I’ll send you my crystal structure if you send me yours!

#6 Gene therapy graduate. After years of producing nothing but gibberish, I’ve shed my exons and ready to express my introns. All I need is a cute vector to introduce me to the right host.

#7 My RNA, I’m sorry I misread your UAAUAAUAA and inserted three tyrosine’s when you repeatedly asked me to stop. Something got lost in the translation. Please forgive me.

#8 Naked DNA with sticky ends seeks kanamycin-resistant plasmid. EcoR1 sites preferred.

#9 Uninhibited virus seeks reason to make me shed my protein coat.

#10 This very selective oligonucleotide has been probing for just the right target for long-term hybridization.

#11 Mature cells seeks some who still enjoys cycling and won’t go apoptotic on me. Let’s fight senescence together!

#12 I’m a prolific progenitor with great potential for growth and self-renewal. Call me if you’re a potent hematopoietic factor who still believes in endless nights of colony stimulation.

#13. I don’t always express myself of the surface, but I’m looking for a signal that you appreciate my complexity. Send me the right message that will penetrate my membranes, turn on my protein expression and release my potential energy. 

These are some of the best jokes ever.

(source)


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